Peter Cook

Location: Room 101, Ashworth Laboratories

Telephone: +44(0)131-650-5488

Research Interests:


Academic History:

2008 – Present
Post-Doctoral Research Fellow, Laboratory of Dr. A. MacDonald, IIIR, University of Edinburgh:
2004– 2008
PhD, Laboratory of Dr. A. Mountford, Dept. of Biology, University of York: Regulation of immune responses following multiple infections with Schistosoma mansoni.
2000 – 2004
BSc Genetics (2i Hon.), University of York. Year placement at Royal Botanical Gardens, Kew, London.



Cook, P.C., Jones, L.H., Jenkins, S.J., Wynn, T.A., Allen, J.E. and MacDonald, A.S. (2012)
Alternatively activated dendritic cells regulate CD4+ T cell polarization in vitro and in vivo. P.N.A.S. 109: 9977-9982.
Ferret-Bernard, S., Castro-Borges, W., Dowle, A.A., Sanin, D.E., Cook, P.C., Turner, J.D., MacDonald, A.S., Thomas, J.R. and Mountford, A.P. (2012)
Plasma membrane proteomes of differentially matured dendritic cells identified by LC-MS/MS combined with iTRAQ labelling. Proteomics. 75: 938-948.
Jenkins, S.J., Ruckerl, D., Cook, P.C., Jones, L.H., Finkelman, F.D., van Rooijen, N., MacDonald, A.S. and Allen, J.E. (2011)
Local macrophage proliferation, rather than recruitment from the blood, is a signature of Th2 inflammation. Science. 332: 1284-1288.
Turner, J.D., Jenkins, G.R., Hogg, K.G., Aynsley, S.A., Paveley, R.A., Cook, P.C., Coles, M.C. and Mountford, A.P. (2011)
CD4+CD25+ regulatory cells contribute to the regulation of colonic Th2 granulomatous pathology caused by schistosome infection. PLoS Neglected Tropical Diseases. 5(8):e1269.
Cook, P.C., Aynsley, S.A., Turner, J.D., Jenkins, G.R., Van Rooijen, N., Leeto, M., Brombacher, F. and Mountford, A.P. (2011)
Multiple helminth infection of the skin causes lymphocyte hypo-responsiveness mediated by Th2 conditioning of dermal myeloid cells. PLoS Pathogens. 7(3):e1001323.
Phythian-Adams, A.T., Cook, P.C., Lundie, R.J., Jones, L.H., Smith, K.A., Barr, T.A., Hochweller, K., Anderton, S.A., Hammerling, G.J., Maizels, R.M. and MacDonald, A.S. (2010)
CD11c depletion severely disrupts Th2 induction and development in vivo. Journal of Experimental Medicine. 207(10):2089-2096.
Paverly, R.A., Aynsley, S.A., Cook, P.C., Turner, J.D. and Mountford, A.P. (2009)
Fluorescent imaging of antigen released by a skin-invading helminth reveals differential uptake and activation profiles by antigen presenting cells. PLoS Neglected Tropical Diseases. 13:3(10):e528