Peter Cook

Location: Room 101, Ashworth Laboratories

Telephone: +44(0)131-650-5488

Email:peter.cook@ed.ac.uk

Research Interests:

 

Academic History:

2008 – Present
Post-Doctoral Research Fellow, Laboratory of Dr. A. MacDonald, IIIR, University of Edinburgh:
 
2004– 2008
PhD, Laboratory of Dr. A. Mountford, Dept. of Biology, University of York: Regulation of immune responses following multiple infections with Schistosoma mansoni.
 
2000 – 2004
BSc Genetics (2i Hon.), University of York. Year placement at Royal Botanical Gardens, Kew, London.

 

Publications:

 
Cook, P.C., Jones, L.H., Jenkins, S.J., Wynn, T.A., Allen, J.E. and MacDonald, A.S. (2012)
Alternatively activated dendritic cells regulate CD4+ T cell polarization in vitro and in vivo. P.N.A.S. 109: 9977-9982.
Ferret-Bernard, S., Castro-Borges, W., Dowle, A.A., Sanin, D.E., Cook, P.C., Turner, J.D., MacDonald, A.S., Thomas, J.R. and Mountford, A.P. (2012)
Plasma membrane proteomes of differentially matured dendritic cells identified by LC-MS/MS combined with iTRAQ labelling. Proteomics. 75: 938-948.
Jenkins, S.J., Ruckerl, D., Cook, P.C., Jones, L.H., Finkelman, F.D., van Rooijen, N., MacDonald, A.S. and Allen, J.E. (2011)
Local macrophage proliferation, rather than recruitment from the blood, is a signature of Th2 inflammation. Science. 332: 1284-1288.
Turner, J.D., Jenkins, G.R., Hogg, K.G., Aynsley, S.A., Paveley, R.A., Cook, P.C., Coles, M.C. and Mountford, A.P. (2011)
CD4+CD25+ regulatory cells contribute to the regulation of colonic Th2 granulomatous pathology caused by schistosome infection. PLoS Neglected Tropical Diseases. 5(8):e1269.
Cook, P.C., Aynsley, S.A., Turner, J.D., Jenkins, G.R., Van Rooijen, N., Leeto, M., Brombacher, F. and Mountford, A.P. (2011)
Multiple helminth infection of the skin causes lymphocyte hypo-responsiveness mediated by Th2 conditioning of dermal myeloid cells. PLoS Pathogens. 7(3):e1001323.
Phythian-Adams, A.T., Cook, P.C., Lundie, R.J., Jones, L.H., Smith, K.A., Barr, T.A., Hochweller, K., Anderton, S.A., Hammerling, G.J., Maizels, R.M. and MacDonald, A.S. (2010)
CD11c depletion severely disrupts Th2 induction and development in vivo. Journal of Experimental Medicine. 207(10):2089-2096.
Paverly, R.A., Aynsley, S.A., Cook, P.C., Turner, J.D. and Mountford, A.P. (2009)
Fluorescent imaging of antigen released by a skin-invading helminth reveals differential uptake and activation profiles by antigen presenting cells. PLoS Neglected Tropical Diseases. 13:3(10):e528