Publications

2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | Book Chapters

2013

Stephen A. Redpath, Nienke van der Werf, Ana M. Cervera, David Gray, Andrew S. MacDonald, Richard M. Maizels and Matthew D. Taylor.
ICOS is required for FoxP3+ regulatory T cell expansion, maintenance and IL-10 production during helminth infection. European Journal of Immunology. In press.

2012

Katie J. Mylonas, Marieke A. Hoeve, Andrew S. MacDonald and Judith E. Allen.
Alternative activation of macrophages by filarial nematodes is MyD88-independent. Immunobiology. In press.
Richard J. Mellanby, Melanie D. Leech, Richard A. O'Connor, Dominika J. Nowakowska, Florian C. Kurschus, Andrew S. MacDonald, Bernd Arnold and Stephen M. Anderton.
1,25(OH)2D Vitamin D suppresses the ability of dendritic cells to drive CNS autoimmune disease. Journal of Neuroinflammation. 9: 248.
Katherine A. Smith, Yvonne Harcus, Natalio Garbi, Gunter J. Hammerling, Andrew S. MacDonald and Rick M. Maizels.
Innate type 2 immunity in helminth infection is induced redundantly and acts autonomously following CD11c+ cell depletion. Infection and Immunity. 80:3481-3489.
Peter C. Cook, Lucy H. Jones, Stephen J. Jenkins, Thomas A. Wynn, Judith E. Allen and Andrew S. MacDonald.
Alternatively activated dendritic cells regulate CD4+ T cell polarization in vitro and in vivo. P.N.A.S. 109: 9977-9982.
Georgia Perona-Wright, Rachel J. Lundie, Stephen J. Jenkins, Lauren M. Webb, Richard K. Grencis and Andrew S. MacDonald.
Concurrent bacterial stimulation alters the function of helminth-activated dendritic cells, resulting in IL-17 induction. Journal of Immunology. 188: 2350-2358.
Stefano Caserta, Norman Nausch, Amy Sawtell, Rebecca Drummond, Tom Barr, Andrew S. MacDonald, Francisca Mutapi and Rose Zamoyska.
Chronic infection drives expression of the inhibitory receptor CD200R, and its ligand CD200, by mouse and human CD4 T cells. PLoS One. 7(4): e35466.
Stephanie Ferret-Bernard, William Castro-Borges, Adam A. Dowle, David E. Sanin, Peter C. Cook, Joseph D. Turner, Andrew S. MacDonald, Jerry R. Thomas and Adrian P. Mountford.
Plasma membrane proteomes of differentially matured dendritic cells identified by LC-MS/MS combined with iTRAQ labelling. Proteomics. 75: 938-948.

2011

Stephen J. Jenkins, Dominik Ruckerl, Peter C. Cook, Lucy H. Jones, Fred D. Finkelman, Nico van Rooijen, Andrew S. MacDonald and Judith E. Allen.
Local macrophage proliferation, rather than recruitment from the blood, is a signature of Th2 inflammation. Science. 332: 1284-1288.
Katherine A. Smith, Kristin Hochweller, Gunter J. Hammerling, Louis Boon, Andrew S. MacDonald and Rick M. Maizels.
Chronic helminth infection promotes immune regulation in vivo through dominance of CD11cloCD103- dendritic cells. Journal of Immunology. 186: 7098-7109.
Nienke van der Werf, Stephen A. Redpath, Alexander T. Phythian-Adams, Miyuki Azuma, Judith E. Allen, Rick M. Maizels, Andrew S. MacDonald and Matthew D. Taylor.
Th2 responses to helminth parasites can be therapeutically enhanced by, but are not dependent upon, GITR-GITRL co-stimulation in vivo. Journal of Immunology. 187: 1411-1420.
Riccardo Sibilano, Giorgia Gri, Barbara Frossi, Claudio Tripodo, Ryo Suzuki, Juan Rivera, Andrew S. MacDonald and Carlo E. Pucillo.
Soluble OX40 mimics regulatory T cell modulatory activity on FcERI-dependent mast cell degranulation. Journal of Leukocyte Biology. 90: 831-838.

2010

Alexander T. Phythian-Adams, Peter C. Cook, Rachel J. Lundie, Lucy H. Jones, Katherine A. Smith, Tom A. Barr, Kristin Hochweller, Stephen M. Anderton, Gunter J. Hammerling, Rick M. Maizels and Andrew S. MacDonald.
CD11c depletion severely disrupts Th2 induction and development in vivo. Journal of Experimental Medicine. 207: 2089-2096.

2009

Georgia Perona-Wright, Stephen J. Jenkins, Richard A. O'Connor, Dimitrios Zienkiewicz, Henry J. McSorley, Rick M. Maizels, Stephen M. Anderton and Andrew S. MacDonald.
A pivotal role for CD40-mediated IL-6 production by dendritic cells during IL-17 induction in vivo. Journal of Immunology. 182: 2808-2815.

2008

Stephen J. Jenkins, Georgia Perona-Wright and Andrew S. MacDonald.
Full development of Th2 immunity requires both innate and adaptive sources of CD154. Journal of Immunology. 180: 8083-8092.
Gemma L. Foster , Tom A. Barr, Andrew J. Grant, Clare E. Bryant, Andrew S. MacDonald, David Gray, Masahiro Yamamoto, Shizuo Akira, Duncan J. Maskell and Pietro Mastroeni.  
Virulent Salmonella enterica infections can be exacerbated by concomitant infection of the host with a live attenuated S. enterica vaccine via Toll-like receptor 4-dependent interleukin-10 production with the involvement of both TRIF and MyD88. Immunology. 124(4): 469-479.
Alan G.F. Worsley, Salome LeibundGut-Landmann, Emma Slack, Li-Kun Phng, Holger Gerhardt, Caetano Reis E Sousa and Andrew S. MacDonald.  
Dendritic cell expression of the Notch ligand jagged2 is not essential for Th2 response induction in vivo. European Journal of Immunology. 38: 1043-1049.
Andrew S. MacDonald and Rick M. Maizels.
Alarming dendritic cells for Th2 induction. Journal of Experimental Medicine. 205: 13-17.

2007

Stephen J. Jenkins, Georgia Perona-Wright, Alan G.F. Worsley, Naoto Ishii and Andrew S. MacDonald.  
Dendritic cell expression of OX40L acts as a costimulatory, not polarizing, signal for optimal Th2 priming and memory induction in vivo. Journal of Immunology. 179: 3515-3523.
Simmi Mahajan, Anna M. Cervera, Megan MacLeod, Simon Fillatreau, Georgia Perona-Wright, S. Meek, A. Smith, Andrew S. MacDonald and David Gray.
The role of ICOS in the development of CD4 T cell help and the re-activation of memory T cells. European Journal of Immunology. 37(7): 1796-1808.

2006

Georgia Perona-Wright, Stephen J. Jenkins, Alison Crawford, David Gray, Edward J. Pearce and Andrew S. MacDonald.
Distinct sources and targets of IL-10 during dendritic cell-driven Th1 and Th2 responses in vivo. European Journal of Immunology. 36(9): 2367-2375.
Georgia Perona-Wright, Stephen J. Jenkins, and Andrew S. MacDonald. 2006.
Dendritic cell activation and function in response to Schistosoma mansoni. International Journal for Parasitology. 36(6): 711-721.

2005

David Artis, Colleen M. Kane, James Fiore, Colby Zaph, Sagi Shapira, Karen Joyce, Andrew MacDonald, Christopher Hunter, Phillip Scott and Edward J. Pearce. 2005.
Dendritic cell-intrinsic expression of NF-κB1 is required to promote optimal Th2 cell differentiation. Journal of Immunology. 174: 7154-7159.

2004

Laura Cervi, Andrew S. MacDonald, Colleen Kane, Florence Dzierszinski, and Edward J. Pearce. 2004.
Cutting Edge: Dendritic cells copulsed with microbial and helminth antigens undergo modified maturation, segregate the antigens to distinct intracellular compartments, and concurrently induce microbe-specific Th1 and helminth-specific Th2 responses. Journal of Immunology. 172: 2016-2020.

2003

Andrew S. MacDonald, P’ng Loke, Robert Martynoga, Ian Dransfield, and Judith E. Allen.  2003.
Cytokine-dependent inflammatory cell recruitment patterns in the peritoneal cavity of mice exposed to the parasitic nematode Brugia malayi.  Medical Microbiology and Immunology. 192: 33-40.
Devon J. Shedlock, Jason K. Whitmire, Joyce Tan, Andrew S. MacDonald, Rafi Ahmed, and Hao Shen. 2003.
Role of CD4 T cell help and costimulation in CD8 T cell responses during Listeria monocytogenes infection. Journal of Immunology. 170: 2053-2063.
Amy D. Straw, Andrew S. MacDonald, Eric Y. Denkers, and Edward J. Pearce. 2003.
CD154 plays a central role in regulating dendritic cell activation during infections that induce Th1 or Th2 responses. Journal of Immunology. 170: 727-734.
Anne C. La Flamme, Andrew S. MacDonald, Clive R. Huxtable, Michael Carroll, and Edward J. Pearce. 2003.
Lack of C3 affects Th2 response development and the sequelae of chemotherapy in schistosomiasis. Journal of Immunology. 170: 470-476.

2002

Edward J. Pearce and Andrew S. MacDonald.  2002. 
The Immunobiology of Schistosomiasis.  Nature Reviews Immunology. 7: 499-511.
Andrew S. MacDonald, Elisabeth A. Patton, Anne C. La Flamme, Maria I. Araujo, Clive R. Huxtable, Beverley Bauman and Edward J. Pearce. 2002.
Impaired Th2 development and increased mortality during Schistosoma mansoni infection in the absence of CD40/CD154 interaction. Journal of Immunology.  168: 4643-4649.
Andrew S. MacDonald and Edward J. Pearce. 2002.
Cutting Edge: Polarized Th cell response induction by transferred antigen-pulsed dendritic cells is dependent on IL-4 or IL-12 production by recipient cells. Journal of Immunology. 168: 3127-3130.
Andrew S. MacDonald, Amy D. Straw, Nicole M. Dalton and Edward J. Pearce. 2002.
Cutting Edge: Th2 response induction by dendritic cells: a role for CD40. Journal of Immunology.  168: 537-540.
Andrew S. MacDonald, Maria Ilma Araujo and Edward J. Pearce.  2002.
The Immunology of Parasitic Helminth Infections.  Infection and Immunity.  70: 427-433.

2001

Andrew S. MacDonald, Amy D. Straw, Beverley Bauman and Edward J. Pearce. 2001.
CD8− dendritic cell activation status plays an integral role in influencing Th2 response development. Journal of Immunology.  167: 1982-1987.
Franco H. Falcone, P’ng Loke, Xingxing Zang, Andrew S. MacDonald, Rick M. Maizels and Judith E. Allen. 2001.
A Brugia malayi homologue of mammalian MIF reveals an important link between macrophages and eosinophil recruitment during nematode infection. Journal of Immunology. 167: 5348-5354.

Book Chapters

Andrew S. MacDonald and Edward J. Pearce.  2006.
Handbook of Dendritic Cells: Biology, Diseases and Therapies.   Chapter 34 – Schistosoma. Wiley-VCH.
Somei Kojima and Andrew S. MacDonald. 2005.
Topley and Wilson’s Microbiology and Microbial Infections (10th edition), Chapters 28 (Schistosomes: General) and 29 (Schistosomes: African). Hodder Arnold.